Is cleaved glucagon-like peptide 1 really inactive? Effects of GLP-1 (9-36) on human adipose stem cells

Is cleaved glucagon-like peptide 1 really inactive? Effects of GLP-1 (9-36) on human adipose stem cells

G Cantini, A Di Franco, E Mannucci, M Luconi - Molecular and cellular …, 2017 - Elsevier
Abstract Glucagon-like peptide 1 (9-36)[GLP-1 (9-36)] is generated by dipeptidyl peptidase-
4 (DPP4) cleavage of the gut incretin hormone, GLP-1 (7-36). Since GLP-1 (9-36) has a very
low affinity for the GLP-1 receptor (GLP-1R), it has so far been considered an inactive form of …


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