[HTML] Peptide-guided functionalization and macrocyclization of bioactive peptidosulfonamides by Pd (II)-catalyzed late-stage C–H activation

[HTML] Peptide-guided functionalization and macrocyclization of bioactive peptidosulfonamides by Pd (II)-catalyzed late-stage C–H activation

J Tang, H Chen, Y He, W Sheng, Q Bai… - Nature communications, 2018 - nature.com
Peptides and peptidomimetics are emerging as an important class of clinic therapeutics.
Here we report a peptide-guided method for the functionalization and macrocyclization of
bioactive peptidosulfonamides by Pd (II)-catalyzed late-stage C–H activation. In this …

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Pepmic Co., Ltd
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