Computation-guided rational design of a peptide motif that reacts with cyanobenzothiazoles via internal cysteine-lysine relay

Computation-guided rational design of a peptide motif that reacts with cyanobenzothiazoles via internal cysteine-lysine relay

SGL Keyser, A Utz, CR Bertozzi - The Journal of organic chemistry, 2018 - ACS Publications
Site-selective protein modification based on covalent reactions of peptide tags and small
molecules is a key capability for basic research as well as for the development of new
therapeutic bioconjugates. Here we describe the computation-guided rational design of a …

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