Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

Botulinum Neurotoxin F Subtypes Cleaving the VAMP-2 Q58–K59 Peptide Bond Exhibit Unique Catalytic Properties and Substrate Specificities

S Sikorra, M Skiba, M Dorner, J Weisemann, M Weil… - Toxins, 2018 - mdpi.com
In the recent past, about 40 botulinum neurotoxin (BoNT) subtypes belonging to serotypes A,
B, E, and F pathogenic to humans were identified among hundreds of independent isolates.
BoNTs are the etiological factors of botulism and represent potential bioweapons; however …

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