MHC Class II Complexes Sample Intermediate States along the Antigenic Peptide Exchange Pathway

MHC Class II Complexes Sample Intermediate States along the Antigenic Peptide Exchange Pathway

S Stolzenberg, M Wieczorek, J Sticht, S Günther… - Biophysical …, 2018 - cell.com
The presentation of antigenic peptide-MHCII complexes (pMHCIIs) for surveillance by T cells
is a well-known immunological concept in vertebrates, yet the conformational dynamics of
antigen exchange remain elusive. By combining NMR-detected H/D exchange with Markov …


For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Jason Lee
jason@pepmic.com
Pepmic Co., Ltd
www.pepmic.com

评论

  1. alfachemistry2018年8月18日 05:23

    n 1996, the development of reagents consisting of soluble MHC class I–peptide complexes, which was applied to detect CD8+ cells by flow cytometry, MHC Peptide

    回复删除

发表评论

此博客中的热门博文

AGTR1 Antibody

Product   AGTR1 Antibody Cat#   100-21-09A Unit/Weight   100 μg Unit Price   $266.00 Species Reactivity   H, M, R Tested Application(s)   E, WB Brief Description   Angiotensin II receptor type 1 Specific Description   Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. AGTR1, the type 1 receptor, is thought to mediate the major cardiovascular effects of angiotensin II and may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. AGTR1 has recently been found to regulate the differentiation of bone marrow-derived monocyte lineage progenitor...
阅读全文

Contact Information - Jason Lee

图片
For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc. *Peptide Salt : TFA, Desalt, Acetate, HCl. *Peptide Purity : From crude to ＞99.5%. *Production Capacity : From mg to kg, with a capacity of synthesizing 15,000 peptides/month. * Peptide Library Synthesis : Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect. Quick Links: Peptide Price Peptide Modification Peptide Library Quote Request Contact Us Contact I...
阅读全文

적당한운동이노화에의한포유동물면역기능의변화에미치는영향

图片
적당한운동이노화에의한포유동물면역기능의변화에미치는영향 김현， 조영무， 고응규， 성환후 - 농업생명과학연구, 2015 - ials.gnu.ac.kr ...  사멸시키는 기능을 가지고 있다. T림프구가 활성화는 항원 펩티드 와 MHC 분자의 복합체가 T 세포 수용체를 통해서 전 달하는 자극과 CD28 과 B7을 경유하는 보조자극 시스템이 필요하다(Wang et al., 2004). 인간 및 설치류의 노화와  ... For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc. *Peptide Salt : TFA, Desalt, Acetate, HCl. *Peptide Purity : From crude to ＞99.5%. *Production Capacity : From mg to kg, with a capacity of s...
阅读全文