Catestatin Prevents Macrophage-Driven Atherosclerosis but Not Arterial Injury–Induced Neointimal Hyperplasia

Catestatin Prevents Macrophage-Driven Atherosclerosis but Not Arterial Injury–Induced Neointimal Hyperplasia

M Kojima, N Ozawa, Y Mori… - Thrombosis and …, 2018 - thieme-connect.com
… Abstract. Catestatin, a catecholamine-release inhibitory peptide, has multiple cardiovascular
activities … Regul Pept 2003; 114 (01) 29-35; 9 Pieroni M, Corti A, Tota B. , et al. Myocardial
production of chromogranin A in human heart: a new regulatory peptide of cardiac function …


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  1. Non-competitive nicotinic cholinergic antagonist that selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM). It blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release, Catestatin

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