Abstract TMP28: Inhibition of Integrin α5β1With the Small Peptide Atn-161 Reduces Infarct Volume and Improves Functional Recovery Through Reduction of Blood …

Abstract TMP28: Inhibition of Integrin α5β1With the Small Peptide Atn-161 Reduces Infarct Volume and Improves Functional Recovery Through Reduction of Blood …

D Edwards, K Salmeron, JF Fraser, GJ Bix - 2018 - Am Heart Assoc
Reperfusion-induced injury after recanalization is exacerbated by blood-brain barrier (BBB)
dysfunction after ischemic stroke. Endothelial cell integrin receptors, specifically the β 1
subtype, play a direct role in BBB dysfunction through regulation of barrier-forming tight …


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  1. creative peptides2018年10月9日 06:41

    ATN-161 is a novel peptide antagonist of integrin α5β1. ATN-161 selectively binds to and blocks the receptor for integrin α5β1, thereby preventing integrin alpha5beta1 binding. ATN 161

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