Peptide Synthesis

Treatment of experimental encephalomyelitis with a  peptide  analogue of myelin basic protein S Brocke, K Gijbels, M Allegretta, I Ferber, C Piercy… - Nature, 1996 - nature.com Abstract FOLLOWING induction of experimental encephalomyelitis with a T-cell clone, L10C1, that is specific for the myelin basic protein epitope p87–99, the inflammatory infiltrate in the central nervous system contains a diverse collection of T cells with heterogeneous For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, ...

Pore formation by the cytotoxic islet amyloid  peptide  amylin TA Mirzabekov, M Lin,  BL Kagan  - Journal of Biological Chemistry, 1996 - ASBMB Abstract Amylin is a 37-amino acid cytotoxic constituent of amyloid deposits found in the islets of Langerhans of patients with type II diabetes. Extracellular accumulation of this peptide  results in damage to insulin-producing β cell membranes and cell death. We report For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte...

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with  peptide  growth factors J Kwon, SR Lee, KS Yang, Y Ahn… - Proceedings of the …, 2004 - National Acad Sciences Abstract Stimulation of cells with various  peptide  growth factors induces the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP 3) through activation of phosphatidylinositol 3- kinase. The action of this enzyme is reversed by that of the tumor suppressor PTEN. With the For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Relat...

Peptide  inhibitors for angiotensin i-converting enzyme from thermolysin digest of dried bonitot K Yokoyama, H Chiba, M Yoshikawa - Bioscience, Biotechnology …, 1992 - Taylor & Francis Dried bonito (Katsuobusi), a Japanese traditional seasoning made of bonito muscle was hydrolyzed by various proteases and the inhibitory activity of the hydrolyzates for angiotensin I-converting enzyme (ACE)[EC 3.4. 15.1] was measured. Among the digests, For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myel...

[HTML]   MHC class II tetramers identify  peptide -specific human CD4 +  T cells proliferating in response to influenza A antigen EJ Novak,  AW Liu , GT Nepom… - The Journal of clinical …, 1999 - Am Soc Clin Investig Selective expansion and activation of a very small number of antigen-specific precursor cells is a remarkable and essential property of the adaptive immune response. Techniques for assessing human antigen-specific T-cell responses are hampered by the requirement for For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related ...

The natriuretic  peptide  system in the brain: implications in the central control of cardiovascular and neuroendocrine functions. H Imura, K Nakao, H Itoh - Frontiers in neuroendocrinology, 1992 - europepmc.org Abstract The natriuretic  peptide  system consists of three endogenous ligands, ie, atrial natriuretic  peptide  (ANP), brain natriuretic  peptide  (BNP), and C-type natriuretic  peptide  (CNP), and at least three subtypes of receptors. All of the peptides and receptors exist in the For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : AC...

Structure–activity analysis of buforin II, a histone H2A-derived antimicrobial  peptide : the proline hinge is responsible for the cell-penetrating ability of buforin II CB Park,  KS Yi , K Matsuzaki… - Proceedings of the …, 2000 - National Acad Sciences Abstract Buforin II is a 21-aa potent antimicrobial  peptide  that forms, in a hydrophobic medium, an amphipathic structure consisting of an N-terminal random coil region (residues 1–4), an extended helical region (residues 5–10), a hinge (residue 11), and a C-terminal For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides ...

The effect of incorporating RGD adhesive  peptide  in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells F Yang , CG Williams,  D Wang ,  H Lee , PN Manson… - Biomaterials, 2005 - Elsevier Abstract Advances in tissue engineering require biofunctional scaffolds that can not only provide cells with structural support, but also interact with cells in a biological manner. To achieve this goal, a frequently used cell adhesion  peptide  Arg–Gly–Asp (RGD) was For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids ...

Anxiolytic-and antidepressant-like effects of the non- peptide  vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of … G Griebel , J Simiand… - Proceedings of the …, 2002 - National Acad Sciences Abstract The limbic localization of the arginine vasopressin V 1b receptor has prompted speculation as to a potential role of this receptor in the control of emotional processes. To investigate this possibility, we have studied the behavioral effects of SSR149415, the first For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors,...

Oxytocin and autistic disorder: alterations in  peptide  forms LA Green, D Fein, C Modahl… - Biological …, 2001 - biologicalpsychiatryjournal.com Abstract Background: Oxytocin (OT) is synthesized as a prohormone that is sequentially processed to peptides. These peptides are the bioactive amidated form (OT) and the C- terminal extended peptides, OT-Gly, OT-Gly-Lys and OT-Gly-Lys-Arg, which are designated For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (M...

Excitatory and inhibitory amino acids and  peptide -induced responses in acutely isolated rat spinal dorsal horn neurons K Murase , PD Ryu, M Randic - Neuroscience letters, 1989 - Elsevier Abstract The responses to excitatory and inhibitory amino acids and peptides were investigated in isolated rat spinal dorsal horn neurons (laminae I–V) of young rats using the whole-cell voltage-clamp technique. The treatment of spinal slices with low concentrations of For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Pept...

Stabilization of the ribonuclease S‐ peptide  α‐helix by trifluoroethanol JW Nelson,  NR Kallenbach  - Proteins: Structure, Function, and …, 1986 - Wiley Online Library Abstract The effects of trifluoroethanol (TFE) on the stability of the α-helix formed by ribonuclease S- peptide , residues 1–19 of ribonuclease A, were studied by measuring circular dichroism as a function of TFE concentration, pH, and temperature. The S- peptide For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Ol...

Self-assembled  peptide -based hydrogels as scaffolds for anchorage-dependent cells M Zhou,  AM Smith , AK Das, NW Hodson, RF Collins… - Biomaterials, 2009 - Elsevier Abstract We report here the design of a biomimetic nanofibrous hydrogel as a 3D-scaffold for anchorage-dependent cells. The  peptide -based bioactive hydrogel is formed through molecular self-assembly and the building blocks are a mixture of two aromatic short  peptide For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, M...