博文

目前显示的是 八月, 2018的博文

Cellular Uptake of A Taurine-Modified, Ester Bond-Decorated D-Peptide Derivative via Dynamin-Based Endocytosis and Macropinocytosis

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Cellular Uptake of A Taurine-Modified, Ester Bond-Decorated D- Peptide  Derivative via Dynamin-Based Endocytosis and Macropinocytosis J Zhou,  X Du , C Berciu, SJ Del Signore,  X Chen … - Molecular Therapy, 2018 - Elsevier Most of the peptides used for promoting cellular uptake bear positive charges. In our previous study, we reported an example of taurine (bearing negative charges in physiological conditions) promoting cellular uptake of D-peptides. Taurine, conjugated to a … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides...

Engineering improved variants of the antifungal peptide histatin 5 with reduced susceptibility to Candida albicans secreted aspartic proteases and enhanced …

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Engineering improved variants of the antifungal  peptide  histatin 5 with reduced susceptibility to Candida albicans secreted aspartic proteases and enhanced … SP Ikonomova, P Moghaddam‐Taaheri… - The FEBS …, 2018 - Wiley Online Library Candida albicans is an opportunistic fungal pathogen and a commensal organism that commonly colonizes mucosal surfaces, including those inside the human mouth. To help control C. albicans, human saliva contains the antifungal  peptide  histatin 5 (Hst-5), which … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitor...

Synergistic effect of cold plasma treatment and RGD peptide coating on cell proliferation over titanium surfaces

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Synergistic effect of cold plasma treatment and RGD  peptide  coating on cell proliferation over titanium surfaces O Karaman , S Kelebek, EA Demirci, F İbiş… - Tissue Engineering and …, 2018 - Springer The aim of this study was to investigate the synergistic effect of cold atmospheric plasma (CAP) treatment and RGD  peptide  coating for enhancing cellular attachment and proliferation over titanium (Ti) surfaces. The surface structure of CAP-treated and RGD … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimic...

The alpha helix 1 from the first conserved region of HIV1 gp120 is reconstructed in the short NQ21 peptide

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The alpha helix 1 from the first conserved region of HIV1 gp120 is reconstructed in the short NQ21  peptide VV Khrustalev , TA Khrustaleva… - Archives of biochemistry …, 2018 - Elsevier Investigations of short peptides that can be used in the next phase of synthetic HIV1 vaccine development are an urgent goal, as well as investigations of peptides that can be used in immunological tests with the aim to check the titer of antibodies against the alpha helix 1 … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptide...

Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM

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Impact of C- Peptide  Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM S Zenz, JK Mader, W Regittnig… - The Journal of …, 2018 - academic.oup.com … Article Navigation. Impact of C- Peptide  Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM. Sabine Zenz. Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Ant...

BG-4, a novel bioactive peptide from momordica charantia, inhibits lipopolysaccharide-induced inflammation in THP-1 human macrophages

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BG-4, a novel bioactive  peptide  from momordica charantia, inhibits lipopolysaccharide-induced inflammation in THP-1 human macrophages LD Jones, P Pangloli,  HB Krishnan , VP Dia - Phytomedicine, 2018 - Elsevier Abstract Background Bitter melon (Momordica charantia) is a commonly used food crop for management of a variety of diseases most notably for control of diabetes, a disease associated with aberrant inflammation. Purpose To evaluate the anti-inflammatory property … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Ant...

Probing the Dynamic Nature of Self‐Assembling Cyclic Peptide–Polymer Nanotubes in Solution and in Mammalian Cells

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Probing the Dynamic Nature of Self‐Assembling Cyclic  Peptide –Polymer Nanotubes in Solution and in Mammalian Cells JY Rho,  JC Brendel , LR MacFarlane… - Advanced Functional …, 2018 - Wiley Online Library Self‐assembling cyclic  peptide –polymer nanotubes have emerged as a fascinating supramolecular system, well suited for a diverse range of biomedical applications. Due to their well‐defined diameter, tunable  peptide  anatomy, and ability to disassemble in situ, they … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related...

Peptide templated Au@ Pd core-shell structures as efficient bi-functional electrocatalysts for both oxygen reduction and hydrogen evolution reactions

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Peptide  templated Au@ Pd core-shell structures as efficient bi-functional electrocatalysts for both oxygen reduction and hydrogen evolution reactions Z Zong, K Xu, D Li,  Z Tang , W He, Z Liu, X Wang… - Journal of …, 2018 - Elsevier Bimetallic core-shell nanostructures have been gaining considerable research attentions recently, mainly thanks to their versatile applications in many fields, including catalysis, electrocatalysis, electronic, sensing and so on. Herein, we demonstrate a  peptide  templated … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhi...

Peptide nanoparticles (PNPs) modified disposable platform for sensitive electrochemical cytosensing of DLD-1 cancer cells

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Peptide  nanoparticles (PNPs) modified disposable platform for sensitive electrochemical cytosensing of DLD-1 cancer cells YT Yaman ,  Ö Akbal , G Bolat, B Bozdogan… - Biosensors and …, 2018 - Elsevier A novel diphenylalaninamid (FFA) based  peptide  nanoparticles (PNPs) modified pencil graphite electrodes (PGEs) for construction of electrochemical cytosensor was demonstrated for the first time in this study. Scanning electron microscopy (SEM) and transmission electron … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Pept...

Investigating inhibitory activity of novel synthetic sericin peptide on α‐D‐glucosidase: kinetics and interaction mechanism study using a docking simulation

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Investigating inhibitory activity of novel synthetic sericin  peptide  on  α ‐D‐glucosidase: kinetics and interaction mechanism study using a docking simulation F Xie, S Wang, L Zhang, J Wu… - Journal of the Science of …, 2018 - Wiley Online Library BACKGROUND We synthesised a novel sericin  peptide  (SP‐GI) with α‐d‐glucosidase inhibitory activity, which has a sequence of SEDSSEVDIDLGN. The kinetics of its  peptide ‐ induced inhibition on α‐d‐glucosidase activity and its interaction mechanism merging with … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptid...

MRI assessment of the postprandial gastrointestinal motility and peptide response in healthy humans

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MRI assessment of the postprandial gastrointestinal motility and  peptide  response in healthy humans A Khalaf, CL Hoad,  A Menys , A Nowak… - …, 2018 - Wiley Online Library Background Feeding triggers inter‐related gastrointestinal (GI) motor,  peptide  and appetite responses. These are rarely studied together due to methodological limitations. Recent MRI advances allow pan‐intestinal, non‐invasive assessment of motility in the undisturbed gut … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Pepti...

[HTML] Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation …

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[HTML]   Expression of a recombinant hybrid antimicrobial  peptide  magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation … M Zhang, Y Shan, H Gao… - Microbial cell …, 2018 - microbialcellfactories.biomedcentral … Antibiotic residues can cause antibiotic resistance in livestock and their food safety-related issues have increased the consumer demand for products lacking these residues. Hence, developing safe and effective antibiotic alternatives is important to the animal feed industry … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides e...