Peptide Synthesis

Calcitonin and amylin receptor  peptide  interaction mechanisms: insights into  peptide -binding modes and allosteric modulation of the calcitonin receptor by receptor … SM Lee,  DL Hay , AA Pioszak - Journal of biological chemistry, 2016 - ASBMB Receptor activity-modifying proteins (RAMP1-3) determine the selectivity of the class B GPCRs calcitonin receptor (CTR) and the CTR-like receptor (CLR), for calcitonin (CT), amylin (Amy), CGRP, and adrenomedullin (AM) peptides. RAMP1/2 alter CLR selectivity for … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhi...

Resistance of Cu(Aβ4–16) to Copper Capture by Metallothionein‐3 Supports a Function for the Aβ4–42  Peptide  as a Synaptic Cu II  Scavenger NE Wezynfeld,  E Stefaniak , K Stachucy… - Angewandte Chemie …, 2016 - Wiley Online Library Aβ4‐42 is a major species of Aβ  peptide  in the brains of both healthy individuals and those affected by Alzheimer's disease. It has recently been demonstrated to bind CuII with an affinity approximately 3000 times higher than the commonly studied Aβ1‐42 and Aβ1‐40 … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhi...

Lipid-based nanoformulations for  peptide  delivery N Matougui, L Boge, AC Groo,  A Umerska … - International journal of …, 2016 - Elsevier Nanoformulations have attracted a lot of attention because of their size-dependent properties. Among the array of nanoformulations, lipid nanoformulations (LNFs) have evoked increasing interest because of the advantages of their high degree of … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptid...

Antioxidant activity of fermented meat sauce and isolation of an associated antioxidant  peptide M Ohata, S Uchida, L Zhou, K Arihara - Food Chemistry, 2016 - Elsevier The present study was carried out to investigate the radical scavenging and antioxidant activities of fermented meat sauce (FMS) against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and the hydroxyl radical (OH-radical), as well as to isolate substances in FMS related to its … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oli...

New development in studies of formyl‐ peptide  receptors: critical roles in host defense L Li, K Chen, Y Xiang, T Yoshimura… - Journal of leukocyte …, 2016 - Wiley Online Library Formyl- peptide  receptors are a family of 7 transmembrane domain, Gi-protein-coupled receptors that possess multiple functions in many pathophysiologic processes because of their expression in a variety of cell types and their capacity to interact with a variety of … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin P...

A dual thermal and photo-switchable shrinking–swelling supramolecular  peptide  dendron gel F Xie, L Qin, M Liu - Chemical Communications, 2016 - pubs.rsc.org A supramolecular dendron gel was fabricated through the co-assembly of an L-glutamic acid terminated amphiphilic dendron and a positively charged azobenzene derivative, which showed a dual thermal and photo-switched reversible volume phase transition or … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycop...

Controlling the physical dimensions of  peptide  nanotubes by supramolecular polymer coassembly L Adler-Abramovich , P Marco,  ZA Arnon … - ACS …, 2016 - ACS Publications Molecular self-assembly of peptides into ordered nanotubes is highly important for various technological applications. Very short  peptide  building blocks, as short as dipeptides, can form assemblies with unique mechanical, optical, piezoelectric, and semiconductive … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, ...

Flunarizine prevents hepatitis C virus membrane fusion in a genotype‐dependent manner by targeting the potential fusion  peptide  within E1 PM Perin, S Haid,  RJP Brown , J Doerrbecker… - …, 2016 - Wiley Online Library To explore mechanisms of hepatitis C viral (HCV) replication we screened a compound library including licensed drugs. Flunarizine, a diphenylmethylpiperazine used to treat migraine, inhibited HCV cell entry in vitro and in vivo in a genotype‐dependent fashion … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides,...

[HTML]   Towards  peptide  vaccines against Zika virus: Immunoinformatics combined with molecular dynamics simulations to predict antigenic epitopes of Zika viral … MU Mirza , S Rafique, A Ali,  M Munir , N Ikram… - Scientific reports, 2016 - nature.com The recent outbreak of Zika virus (ZIKV) infection in Brazil has developed to a global health concern due to its likely association with birth defects (primary microcephaly) and neurological complications. Consequently, there is an urgent need to develop a vaccine to … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptid...

A  peptide -based mechano-sensitive, proteolytically stable hydrogel with remarkable antibacterial properties A Baral ,  S Roy ,  S Ghosh ,  D Hermida-Merino … - Langmuir, 2016 - ACS Publications A long-chain amino acid containing dipeptide has been found to form a hydrogel in phosphate buffer whose pH ranges from 6.0 to 8.8. The hydrogel formed at pH 7.46 has been characterized by small-angle X-ray scattering (SAXS), wide-angle powder X-ray … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Ape...

Peptide -decorated gold nanoparticles as functional nano-capping agent of mesoporous silica container for targeting drug delivery G Chen , Y Xie,  R Peltier ,  H Lei , P Wang… - … applied materials & …, 2016 - ACS Publications A stimuli-responsive drug delivery system (DDS) with bioactive surface is constructed by end- capping mesoporous silica nanoparticles (MSNs) with functional  peptide -coated gold nanoparticles (GNPs). MSNs are first functionalized with acid-labile α-amide-β-carboxyl … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amy...

[HTML]   Common molecular mechanism of amyloid pore formation by Alzheimer's β-amyloid  peptide  and α-synuclein C Di Scala, N Yahi, S Boutemeur, A Flores… - Scientific reports, 2016 - nature.com Calcium-permeable pores formed by small oligomers of amyloid proteins are the primary pathologic species in Alzheimer's and Parkinson's diseases. However, the molecular mechanisms underlying the assembly of these toxic oligomers in the plasma membrane of … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Ape...