Peptide Synthesis

[HTML]   Computational analysis of envelope glycoproteins from diverse geographical isolates of bovine leukemia virus identifies highly conserved  peptide  motifs A Pluta, LM Albritton, M Rola-Łuszczak… - …, 2018 - retrovirology.biomedcentral.com Bovine leukemia virus (BLV) is a deltaretrovirus infecting bovine B cells and causing enzootic bovine leucosis. The SU or surface subunit, gp51, of its envelope glycoprotein is involved in receptor recognition and virion attachment. It contains the major neutralizing and … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inh...

[HTML]   Self-assembling  peptide  hydrogel enables instant epicardial coating of the heart with mesenchymal stromal cells for the treatment of heart failure Y Ichihara, M Kaneko, K Yamahara, M Koulouroudias… - Biomaterials, 2018 - Elsevier Transplantation of mesenchymal stromal cells (MSCs) is an emerging therapy for the treatment of heart failure. However, the delivery method of MSC is currently suboptimal. The use of self-assembling  peptide  hydrogels, including PuraMatrix®(PM; 3-D Matrix, Ltd), has … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inh...

[D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, small molecule synthetic  peptide  leptin mimetics, improve glycemic control in diet-induced obese (DIO) mice A Wang, BM Anderson, ZM Novakovic, P Grasso - Peptides, 2018 - Elsevier We have previously shown that following oral delivery in dodecyl maltoside (DDM),[D-Leu-4]- OB3 and its myristic acid conjugate, MA-[D-Leu-4]-OB3, improved energy balance and glucose homeostasis in genetically obese/diabetic mouse models. More recently, we have … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, An...

Intracellular  Peptide  Self-Assembly: A Biomimetic Approach for  in Situ  Nano-drug Preparation W Du, X Hu, W Wei, G Liang - Bioconjugate chemistry, 2018 - ACS Publications Most of the nano-drugs are pre-prepared by encapsulating or loading the drugs with nano- carriers (eg, dendrimers, liposomes, micelles, and polymeric nanoparticles). However, besides the low bioavailability and fast excretion of the nano-drugs in vivo, nano-carriers … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin ...

Peptide  deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts R Grzela, J Nusbaum, S Fieulaine, F Lavecchia… - … et Biophysica Acta (BBA …, 2018 - Elsevier Unexpected  peptide  deformylase (PDF) genes were recently retrieved in numerous marine phage genomes. While various hypotheses dealing with the occurrence of these intriguing sequences have been made, no further characterization and functional studies have been … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloid...

Peptide  functionalized metallic nanoconstructs: Synthesis, structural characterization and antimicrobial evaluation M Bajaj, S Pandey, N Wangoo… - … Biomaterials Science & …, 2018 - ACS Publications Biomolecule based conjugation of metallic nanoparticles is an important area of research lately especially considering the role of such nanoconjugates in diverse applications. Herein, synthesis of cationic dipeptide conjugated gold/silver nanoparticles through covalent … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Ant...

Immobilization of Staphylococcus aureus Sortase A on Chitosan Particles and Its Applications in  Peptide -to- Peptide  Ligation and  Peptide  Cyclization M Yang, H Hong, S Liu, X Zhao, Z Wu - Molecules, 2018 - mdpi.com Chitosan macro-particles prepared by the neutralization method were applied to Sortase A (SrtA) immobilization using glutaraldehyde as a crosslinking agent. The particles were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related P...

PEPTIDE  FOR TARGETING AUTOPHAGIC CELLS AND USE THEREOF B Lee, B Acharya - US Patent App. 15/687,219, 2018 - freepatentsonline.com The present invention relates to an autophagic cell targeted  peptide  and its use. More particularly, the present invention relates to a polypeptide comprising an amino acid sequence represented by the general formula (I) and specifically binding to an autophagic … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG...

A Novel Membrane  Peptide  that Inhibits Cell Migration by Activation of the Receptor Tyrosine Kinase EphA2 JM Westerfield, DS Alves, X Shi, VP Nguyen… - Biophysical …, 2018 - cell.com Misregulation of the signaling axis formed by EphA2 and its ligand, ephrinA1, causes aberrant cell-cell contacts and leads to cellular transformation and malignancy in cancer. However, the activation mechanism of EphA2 is poorly understood. Also, solid tumors … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin P...

Attacking Ras-driven cancers: Engineering a  peptide  inhibitor for Cdc42 GJN Tetley - 2018 - repository.cam.ac.uk Prior work has indicated that preventing Cdc42 interacting with its downstream effector proteins can reverse Ras-driven oncogenesis. The experiments demonstrating this used the G protein binding region (GBD) of the Cdc42-specific effector ACK, which is 42 amino acids … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Protein...

A small  peptide  derived from BMP-9 can increase the effect of bFGF and NGF on SH-SY5Y cells differentiation MA Lauzon, N Faucheux - Molecular and Cellular Neuroscience, 2018 - Elsevier The current aging of the world population will increase the number of people suffering from brain degenerative diseases such as Alzheimer's disease (AD). There are evidence showing that the use of growth factors such as BMP-9 could restored cognitive function as it … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apeli...

Identification of Individual Bacterial Cells through the Intermolecular Interactions with  Peptide -Functionalized Solid-State Pores M Tsutsui, M Tanaka, T Marui, K Yokota… - Analytical …, 2018 - ACS Publications Bioinspired pore sensing for selective detection of flagellated bacteria was investigated. The Au micropore wall surface was modified with a synthetic  peptide  designed from toll-like receptor 5 (TLR5) to mimic the pathogen-recognition capability. We found that … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptid...

[HTML]   Mechanistic insights into remodeled Tau-derived PHF6  peptide  fibrils by Naphthoquinone-Tryptophan hybrids VG KrishnaKumar, A Paul, E Gazit, D Segal - Scientific reports, 2018 - nature.com Intra-cellular tau protein tangles and extra-cellular β-amyloid plaques are hallmarks of Alzheimer's disease (AD), characterized by the conversion of natively unfolded monomeric protein/ peptide  into misfolded β-sheet rich aggregates. Therefore, inhibiting the aggregation … For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides,...