Peptide Synthesis

Affinity capillary electrophoresis and density functional theory study of noncovalent interactions of cyclic  peptide  [Gly6]‐antamanide with small cations S Pangavhane, S Böhm, E Makrlík,  P Ruzza … - …, 2017 - Wiley Online Library Abstract ACE and density functional theory (DFT) were employed to study the noncovalent interactions of cyclic decapeptide glycine-6-antamanide ([Gly 6] AA), synthetic derivative of native antamanide  peptide  from the deadly poisonous fungus Amanita phaloides, with small For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, A...

Osteogenesis and mineralization of mesenchymal stem cells in collagen type I‐based recombinant  peptide  scaffolds KM Pawelec, D Confalonieri, F Ehlicke… - … Research Part A, 2017 - Wiley Online Library Abstract Recombinant peptides have the power to harness the inherent biocompatibility of natural macromolecules, while maintaining a defined chemistry for use in tissue engineering. Creating scaffolds from peptides requires stabilization via crosslinking, a For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides,...

Proton Conduction in a Tyrosine‐Rich  Peptide /Manganese Oxide Hybrid Nanofilm J Lee , IR Choe,  YO Kim , SD Namgung… - Advanced Functional …, 2017 - Wiley Online Library Abstract Proton conduction is an essential process that regulates an integral part of several enzymatic catalyses and bioenergetics. Proton flows in biological entities are sensitively controlled by several mechanisms. To understand and manipulate proton conduction in For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Mye...

Optimisation of the antifungal potency of the amidated  peptide  H-Orn-Orn-Trp-Trp-NH2 against food contaminants T Thery, Y O'Callaghan, N O'Brien, EK Arendt - International journal of food …, 2018 - Elsevier Abstract The design of novel efficient antimicrobial peptides (AMPs) faces several issues, such as cost of synthesis, proteolytic stability or cytotoxicity. The identification of key determinants involved in the activity of AMPs, such as cationicity and amphipathicity, For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antim...

Foldectures: 3D Molecular Architectures from Self-Assembly of  Peptide  Foldamers SH Yoo,  HS Lee  - Accounts of Chemical Research, 2017 - ACS Publications Conspectus The wide range of fascinating supramolecular architectures found in nature, from DNA double helices to giant protein shells, inspires researchers to mimic the diverse shapes and functions of natural systems. Thus, a variety of artificial molecular platforms have For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligod...

Neurochemical evidence that cocaine-and amphetamine-regulated transcript (CART) 55–102  peptide  modulates the dopaminergic reward system by decreasing the … A Rakovska, M Baranyi, K Windisch… - Brain research …, 2017 - Elsevier Abstract CART (Cocaine-and Amphetamine-Regulated Transcript)  peptide  is a neurotransmitter naturally occurring in the CNS and found mostly in nucleus accumbens, ventrotegmental area, ventral pallidum, amygdalae and striatum, brain regions associated For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Relate...

[HTML]   Peptide -based scaffolds support human cortical progenitor graft integration to reduce atrophy and promote functional repair in a model of stroke FA Somaa,  TY Wang ,  JC Niclis ,  KF Bruggeman … - Cell reports, 2017 - Elsevier Summary Stem cell transplants offer significant hope for brain repair following ischemic damage. Pre-clinical work suggests that therapeutic mechanisms may be multi-faceted, incorporating bone-fide circuit reconstruction by transplanted neurons, but also protection/ For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids...

[HTML]   A scavenger  peptide  prevents methylglyoxal induced pain in mice S Brings, T Fleming, S De Buhr, B Beijer… - … et Biophysica Acta (BBA …, 2017 - Elsevier Abstract The reactive metabolite methylglyoxal (MG) has been identified as mediator of pain. Scavenging of free MG and the prevention of MG-derived post-translational modifications may provide a useful therapeutic treatment. An arginine-rich, fatty acid coupled, cyclic For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides,...

Tumor-targeted supramolecular nanoparticles self-assembled from a ruthenium-β-cyclodextrin complex and an adamantane-functionalized  peptide SS Xue,  CP Tan , MH Chen,  JJ Cao … - Chemical …, 2017 - pubs.rsc.org We report here a supramolecular strategy to assemble a cyclodextrin-functionalized anticancer Ru (II) complex with an adamantane-appended tumor-targeting  peptide  into discrete and stable phosphorescent nanostructures that can induce cell death in integrin For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides,...

… for Different Treatment Intensification Approaches in Patients with Type 2 Diabetes Uncontrolled on Basal Insulin: Adding Glucagon-Like  Peptide -1 Receptor Agonists … P Levin, T Fan, X Song, D Nero, B Davis… - Endocrine …, 2017 - journals.aace.com Abstract Objective—Not all patients with type 2 diabetes achieve the recommended glycated hemoglobin A1c (A1C) levels after adequate titration of basal insulin (BI). Current intensification approaches include addition of rapid-acting insulin (RAI) or a glucagon-like For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibi...

Ligand discovery for a  peptide -binding GPCR by structure-based screening of fragment-and lead-like chemical libraries A Ranganathan , P Heine, A Rudling… - ACS chemical …, 2017 - ACS Publications Peptide -recognizing G protein-coupled receptors (GPCRs) are promising therapeutic targets but often resist drug discovery efforts. Determination of crystal structures for  peptide -binding GPCRs has provided opportunities to explore structure-based methods in lead For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptides : ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptid...

Expression and actions of corticotropin-releasing factor/diuretic hormone-like  peptide  (CDLP) and teneurin C-terminal associated  peptide  (TCAP) in the vase tunicate … LD Andrea, AHR Hsieh, AHM Hsieh… - General and …, 2017 - Elsevier Abstract Teneurin C-terminal associated  peptide  (TCAP) is a neuropeptide that bears some structural similarity to the corticotropin-releasing factor (CRF) family of peptides. TCAP and CRF are both implicated in the regulation of stress-related behaviors, as established in For custom peptides, please visit  www.pepmic.com . Our peptide services including but not limited to: *Peptide Synthesis : From short peptides to long peptides, linear peptides to cyclic peptides. * Peptide Modifications : Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc. *Catalog Peptide...